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Recurrent bottlenecks in the malaria life cycle obscure signals of positive selection

Detecting signals of selection in the genome of malaria parasites is a key to identify targets for drug and vaccine development. Malaria parasites have a unique life cycle alternating between vector and host organism with a population bottleneck at each transition. These recurrent bottlenecks could...

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Detalles Bibliográficos
Autores principales: CHANG, HSIAO-HAN, HARTL, DANIEL L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139472/
https://www.ncbi.nlm.nih.gov/pubmed/24560397
http://dx.doi.org/10.1017/S0031182014000067