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Identification of microRNAs specific for high producer CHO cell lines using steady-state cultivation

MicroRNAs are short non-coding RNAs that play an important role in the regulation of gene expression. Hence, microRNAs are considered as potential targets for engineering of Chinese hamster ovary (CHO) cells to improve recombinant protein production. Here, we analyzed and compared the microRNA expre...

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Detalles Bibliográficos
Autores principales: Maccani, Andreas, Hackl, Matthias, Leitner, Christian, Steinfellner, Willibald, Graf, Alexandra B., Tatto, Nadine E., Karbiener, Michael, Scheideler, Marcel, Grillari, Johannes, Mattanovich, Diethard, Kunert, Renate, Borth, Nicole, Grabherr, Reingard, Ernst, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139590/
https://www.ncbi.nlm.nih.gov/pubmed/25052466
http://dx.doi.org/10.1007/s00253-014-5911-4