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Identification of microRNAs specific for high producer CHO cell lines using steady-state cultivation
MicroRNAs are short non-coding RNAs that play an important role in the regulation of gene expression. Hence, microRNAs are considered as potential targets for engineering of Chinese hamster ovary (CHO) cells to improve recombinant protein production. Here, we analyzed and compared the microRNA expre...
Autores principales: | Maccani, Andreas, Hackl, Matthias, Leitner, Christian, Steinfellner, Willibald, Graf, Alexandra B., Tatto, Nadine E., Karbiener, Michael, Scheideler, Marcel, Grillari, Johannes, Mattanovich, Diethard, Kunert, Renate, Borth, Nicole, Grabherr, Reingard, Ernst, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139590/ https://www.ncbi.nlm.nih.gov/pubmed/25052466 http://dx.doi.org/10.1007/s00253-014-5911-4 |
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