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Evidence supporting the existence of a NUPR1-like family of helix-loop-helix chromatin proteins related to, yet distinct from, AT hook-containing HMG proteins

NUPR1, a small chromatin protein, plays a critical role in cancer development, progression, and resistance to therapy. Here, using a combination of structural bioinformatics and molecular modeling methods, we report several novel findings that enhance our understanding of the biochemical function of...

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Detalles Bibliográficos
Autores principales: Urrutia, Raul, Velez, Gabriel, Lin, Marisa, Lomberk, Gwen, Neira, Jose Luis, Iovanna, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139591/
https://www.ncbi.nlm.nih.gov/pubmed/25056123
http://dx.doi.org/10.1007/s00894-014-2357-7