Cargando…
Evidence supporting the existence of a NUPR1-like family of helix-loop-helix chromatin proteins related to, yet distinct from, AT hook-containing HMG proteins
NUPR1, a small chromatin protein, plays a critical role in cancer development, progression, and resistance to therapy. Here, using a combination of structural bioinformatics and molecular modeling methods, we report several novel findings that enhance our understanding of the biochemical function of...
Autores principales: | Urrutia, Raul, Velez, Gabriel, Lin, Marisa, Lomberk, Gwen, Neira, Jose Luis, Iovanna, Juan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139591/ https://www.ncbi.nlm.nih.gov/pubmed/25056123 http://dx.doi.org/10.1007/s00894-014-2357-7 |
Ejemplares similares
-
Pivotal Role of the Chromatin Protein Nupr1 in Kras-Induced Senescence and Transformation
por: Grasso, Daniel, et al.
Publicado: (2015) -
Targeting the Stress-Induced Protein NUPR1 to Treat Pancreatic Adenocarcinoma
por: Santofimia-Castaño, Patricia, et al.
Publicado: (2019) -
An overview of the basic helix-loop-helix proteins
por: Jones, Susan
Publicado: (2004) -
NUPR1 protects against hyperPARylation-dependent cell death
por: Santofimia-Castaño, Patricia, et al.
Publicado: (2022) -
The Evolution of the Neural Basic Helix-Loop-Helix Proteins
por: Vervoort, Michel, et al.
Publicado: (2002)