The Notch pathway controls fibrotic and regenerative repair in the adult heart

AIMS: In the adult heart, Notch signalling regulates the response to injury. Notch inhibition leads to increased cardiomyocyte apoptosis, and exacerbates the development of cardiac hypertrophy and fibrosis. The role of Notch in the mesenchymal stromal cell fraction, which contains cardiac fibroblast...

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Detalles Bibliográficos
Autores principales: Nemir, Mohamed, Metrich, Mélanie, Plaisance, Isabelle, Lepore, Mario, Cruchet, Steeve, Berthonneche, Corinne, Sarre, Alexandre, Radtke, Freddy, Pedrazzini, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139705/
https://www.ncbi.nlm.nih.gov/pubmed/23166366
http://dx.doi.org/10.1093/eurheartj/ehs269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139705/
https://www.ncbi.nlm.nih.gov/pubmed/23166366
http://dx.doi.org/10.1093/eurheartj/ehs269

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