Inhibition of TRPM7 Channels Reduces Degranulation and Release of Cytokines in Rat Bone Marrow-Derived Mast Cells

Background: mast cells play an important role in airway inflammation in asthma. The transient receptor potential melastatin-like 7 (TRPM7) channel is expressed in primary human lung mast cells and plays a critical role for cell survival. This study aimed to investigate the role of TRPM7 on degranula...

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Detalles Bibliográficos
Autores principales: Huang, Linjie, Ng, Ngai-Mui, Chen, Ming, Lin, Xiaoling, Tang, Tiantian, Cheng, Huihua, Yang, Cheng, Jiang, Shanping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139816/
https://www.ncbi.nlm.nih.gov/pubmed/24995695
http://dx.doi.org/10.3390/ijms150711817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139816/
https://www.ncbi.nlm.nih.gov/pubmed/24995695
http://dx.doi.org/10.3390/ijms150711817

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