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Inhibition of TRPM7 Channels Reduces Degranulation and Release of Cytokines in Rat Bone Marrow-Derived Mast Cells
Background: mast cells play an important role in airway inflammation in asthma. The transient receptor potential melastatin-like 7 (TRPM7) channel is expressed in primary human lung mast cells and plays a critical role for cell survival. This study aimed to investigate the role of TRPM7 on degranula...
Autores principales: | Huang, Linjie, Ng, Ngai-Mui, Chen, Ming, Lin, Xiaoling, Tang, Tiantian, Cheng, Huihua, Yang, Cheng, Jiang, Shanping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139816/ https://www.ncbi.nlm.nih.gov/pubmed/24995695 http://dx.doi.org/10.3390/ijms150711817 |
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