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Proteomic Analyses Reveal that Sky1 Modulates Apoptosis and Mitophagy in Saccharomyces cerevisiae Cells Exposed to Cisplatin

Sky1 is the only member of the SR (Serine–Arginine) protein kinase family in Saccharomyces cerevisiae. When yeast cells are treated with the anti-cancer drug cisplatin, Sky1 kinase activity is necessary to produce the cytotoxic effect. In this study, proteome changes in response to this drug and/or...

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Detalles Bibliográficos
Autores principales: Rodríguez-Lombardero, Silvia, Rodríguez-Belmonte, M. Esther, González-Siso, M. Isabel, Vizoso-Vázquez, Ángel, Valdiglesias, Vanessa, Laffón, Blanca, Cerdán, M. Esperanza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139861/
https://www.ncbi.nlm.nih.gov/pubmed/25029545
http://dx.doi.org/10.3390/ijms150712573