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Proteomic Analyses Reveal that Sky1 Modulates Apoptosis and Mitophagy in Saccharomyces cerevisiae Cells Exposed to Cisplatin
Sky1 is the only member of the SR (Serine–Arginine) protein kinase family in Saccharomyces cerevisiae. When yeast cells are treated with the anti-cancer drug cisplatin, Sky1 kinase activity is necessary to produce the cytotoxic effect. In this study, proteome changes in response to this drug and/or...
Autores principales: | Rodríguez-Lombardero, Silvia, Rodríguez-Belmonte, M. Esther, González-Siso, M. Isabel, Vizoso-Vázquez, Ángel, Valdiglesias, Vanessa, Laffón, Blanca, Cerdán, M. Esperanza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139861/ https://www.ncbi.nlm.nih.gov/pubmed/25029545 http://dx.doi.org/10.3390/ijms150712573 |
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