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Alzheimer’s Disease—A Panorama Glimpse

The single-mutation of genes associated with Alzheimer’s disease (AD) increases the production of Aβ peptides. An elevated concentration of Aβ peptides is prone to aggregation into oligomers and further deposition as plaque. Aβ plaques and neurofibrillary tangles are two hallmarks of AD. In this rev...

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Detalles Bibliográficos
Autores principales: Zhao, Li Na, Lu, Lanyuan, Chew, Lock Yue, Mu, Yuguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139864/
https://www.ncbi.nlm.nih.gov/pubmed/25032844
http://dx.doi.org/10.3390/ijms150712631