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Cordycepin Down-Regulates Multiple Drug Resistant (MDR)/HIF-1α through Regulating AMPK/mTORC1 Signaling in GBC-SD Gallbladder Cancer Cells

Gallbladder cancer is the most common malignancy of the bile duct, with low 5-year survival rate and poor prognosis. Novel effective treatments are urgently needed for the therapy of this disease. Here, we showed that cordycepin, the bioactive compound in genus Cordyceps, induced growth inhibition a...

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Detalles Bibliográficos
Autores principales: Wu, Wei-Ding, Hu, Zhi-Ming, Shang, Min-Jie, Zhao, Da-Jian, Zhang, Cheng-Wu, Hong, De-Fei, Huang, Dong-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139874/
https://www.ncbi.nlm.nih.gov/pubmed/25046749
http://dx.doi.org/10.3390/ijms150712778