Cargando…
Cordycepin Down-Regulates Multiple Drug Resistant (MDR)/HIF-1α through Regulating AMPK/mTORC1 Signaling in GBC-SD Gallbladder Cancer Cells
Gallbladder cancer is the most common malignancy of the bile duct, with low 5-year survival rate and poor prognosis. Novel effective treatments are urgently needed for the therapy of this disease. Here, we showed that cordycepin, the bioactive compound in genus Cordyceps, induced growth inhibition a...
Autores principales: | Wu, Wei-Ding, Hu, Zhi-Ming, Shang, Min-Jie, Zhao, Da-Jian, Zhang, Cheng-Wu, Hong, De-Fei, Huang, Dong-Sheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139874/ https://www.ncbi.nlm.nih.gov/pubmed/25046749 http://dx.doi.org/10.3390/ijms150712778 |
Ejemplares similares
-
Curcumin induces apoptosis in gallbladder carcinoma cell line GBC-SD cells
por: Liu, Tian-Yu, et al.
Publicado: (2013) -
MPZL1 is highly expressed in advanced gallbladder carcinoma and promotes the aggressive behavior of human gallbladder carcinoma GBC-SD cells
por: Liu, Xiaolei, et al.
Publicado: (2019) -
APEX1 predicts poor prognosis of gallbladder cancer and affects biological properties of CD133(+) GBC-SD cells via upregulating Jagged1
por: Wu, Zhengchun, et al.
Publicado: (2023) -
TLR4 counteracts BVRA signaling in human leukocytes via differential regulation of AMPK, mTORC1 and mTORC2
por: Zhang, Zhiyong, et al.
Publicado: (2019) -
SUMOylation of AMPKα1 by PIAS4 specifically regulates mTORC1 signalling
por: Yan, Yan, et al.
Publicado: (2015)