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Genetic evidence suggests that Spata22 is required for the maintenance of Rad51 foci in mammalian meiosis

Meiotic nodules are the sites of double-stranded DNA break repair. Rpa is a single-stranded DNA-binding protein, and Rad51 is a protein that assists in the repair of DNA double strand breaks. The localisation of Rad51 to meiotic nodules before the localisation of Rpa in mice introduces the issue of...

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Detalles Bibliográficos
Autores principales: Ishishita, Satoshi, Matsuda, Yoichi, Kitada, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139951/
https://www.ncbi.nlm.nih.gov/pubmed/25142975
http://dx.doi.org/10.1038/srep06148