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Genetic evidence suggests that Spata22 is required for the maintenance of Rad51 foci in mammalian meiosis
Meiotic nodules are the sites of double-stranded DNA break repair. Rpa is a single-stranded DNA-binding protein, and Rad51 is a protein that assists in the repair of DNA double strand breaks. The localisation of Rad51 to meiotic nodules before the localisation of Rpa in mice introduces the issue of...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139951/ https://www.ncbi.nlm.nih.gov/pubmed/25142975 http://dx.doi.org/10.1038/srep06148 |