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Genetic evidence suggests that Spata22 is required for the maintenance of Rad51 foci in mammalian meiosis
Meiotic nodules are the sites of double-stranded DNA break repair. Rpa is a single-stranded DNA-binding protein, and Rad51 is a protein that assists in the repair of DNA double strand breaks. The localisation of Rad51 to meiotic nodules before the localisation of Rpa in mice introduces the issue of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139951/ https://www.ncbi.nlm.nih.gov/pubmed/25142975 http://dx.doi.org/10.1038/srep06148 |