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The dual nature of mismatch repair as antimutator and mutator: for better or for worse

DNA is constantly under attack by a number of both exogenous and endogenous agents that challenge its integrity. Among the mechanisms that have evolved to counteract this deleterious action, mismatch repair (MMR) has specialized in removing DNA biosynthetic errors that occur when replicating the gen...

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Detalles Bibliográficos
Autores principales: Bak, Sara Thornby, Sakellariou, Despoina, Pena-Diaz, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139959/
https://www.ncbi.nlm.nih.gov/pubmed/25191341
http://dx.doi.org/10.3389/fgene.2014.00287