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Investigating of microsatellites instability in patients with hereditary non-polyposis colorectal cancer in Isfahan

BACKGROUND: Microsatellites or simple sequence repeats are repeating sequences of deoxyribonucleic acid (DNA). Mutation in mismatch repair (MMR) genes can cause microsatellites instability (MSI) in some tumors. In familial disorder of hereditary non-polyposis colorectal cancer (HNPCC), there is a de...

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Detalles Bibliográficos
Autores principales: Homayouni, Vida, Salehi, Mansour, Kazemi, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139975/
https://www.ncbi.nlm.nih.gov/pubmed/25161992
http://dx.doi.org/10.4103/2277-9175.135162