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Metabolite Traits and Genetic Risk Provide Complementary Information for the Prediction of Future Type 2 Diabetes

OBJECTIVE: A genetic risk score (GRS) comprised of single nucleotide polymorphisms (SNPs) and metabolite biomarkers have each been shown, separately, to predict incident type 2 diabetes. We tested whether genetic and metabolite markers provide complementary information for type 2 diabetes prediction...

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Detalles Bibliográficos
Autores principales: Walford, Geoffrey A., Porneala, Bianca C., Dauriz, Marco, Vassy, Jason L., Cheng, Susan, Rhee, Eugene P., Wang, Thomas J., Meigs, James B., Gerszten, Robert E., Florez, Jose C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140156/
https://www.ncbi.nlm.nih.gov/pubmed/24947790
http://dx.doi.org/10.2337/dc14-0560