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Size-dependent accumulation of particles in lysosomes modulates dendritic cell function through impaired antigen degradation
INTRODUCTION: Nanosized particles may enable therapeutic modulation of immune responses by targeting dendritic cell (DC) networks in accessible organs such as the lung. To date, however, the effects of nanoparticles on DC function and downstream immune responses remain poorly understood. METHODS: Bo...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140235/ https://www.ncbi.nlm.nih.gov/pubmed/25152619 http://dx.doi.org/10.2147/IJN.S64353 |