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The Peptide-binding Cavity Is Essential for Als3-mediated Adhesion of Candida albicans to Human Cells

The adhesive phenotype of Candida albicans contributes to its ability to colonize the host and cause disease. Als proteins are one of the most widely studied C. albicans virulence attributes; deletion of ALS3 produces the greatest reduction in adhesive function. Although adhesive activity is thought...

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Detalles Bibliográficos
Autores principales: Lin, Jing, Oh, Soon-Hwan, Jones, Rhian, Garnett, James A., Salgado, Paula S., Rusnakova, Sophia, Matthews, Steve J., Hoyer, Lois L., Cota, Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140257/
https://www.ncbi.nlm.nih.gov/pubmed/24802757
http://dx.doi.org/10.1074/jbc.M114.547877