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One-Pot Isomerization–Cross Metathesis–Reduction (ICMR) Synthesis of Lipophilic Tetrapeptides

[Image: see text] An efficient, versatile and rapid method toward homologue series of lipophilic tetrapeptide derivatives (herein, the opioid peptides H-TIPP-OH and H-DIPP-OH) is reported. High atom economy and a minimal number of synthetic steps resulted from a one-pot tandem isomerization-cross me...

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Detalles Bibliográficos
Autores principales: Jida, Mouhamad, Betti, Cecilia, Schiller, Peter W., Tourwé, Dirk, Ballet, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140390/
https://www.ncbi.nlm.nih.gov/pubmed/24906051
http://dx.doi.org/10.1021/co500020a