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Investigation of aromatase inhibitory activity of metal complexes of 8-hydroxyquinoline and uracil derivatives

PURPOSE: Estrogens play important roles in the pathogenesis and progression of breast cancer as well as estrogen-related diseases. Aromatase is a key enzyme in the rate-limiting step of estrogen production, in which its inhibition is one strategy for controlling estrogen levels to improve prognosis...

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Detalles Bibliográficos
Autores principales: Prachayasittikul, Veda, Pingaew, Ratchanok, Nantasenamat, Chanin, Prachayasittikul, Supaluk, Ruchirawat, Somsak, Prachayasittikul, Virapong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140444/
https://www.ncbi.nlm.nih.gov/pubmed/25152615
http://dx.doi.org/10.2147/DDDT.S67300