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Investigation of aromatase inhibitory activity of metal complexes of 8-hydroxyquinoline and uracil derivatives
PURPOSE: Estrogens play important roles in the pathogenesis and progression of breast cancer as well as estrogen-related diseases. Aromatase is a key enzyme in the rate-limiting step of estrogen production, in which its inhibition is one strategy for controlling estrogen levels to improve prognosis...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140444/ https://www.ncbi.nlm.nih.gov/pubmed/25152615 http://dx.doi.org/10.2147/DDDT.S67300 |