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Rapid Synthesis of Polyprenylated Acylphloroglucinol Analogs via Dearomative Conjunctive Allylic Annulation

[Image: see text] Polyprenylated acylphloroglucinols (PPAPs) are structurally complex natural products with promising biological activities. Herein, we present a biosynthesis-inspired, diversity-oriented synthesis approach for rapid construction of PPAP analogs via double decarboxylative allylation...

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Detalles Bibliográficos
Autores principales: Grenning, Alexander J., Boyce, Jonathan H., Porco, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140454/
https://www.ncbi.nlm.nih.gov/pubmed/25061804
http://dx.doi.org/10.1021/ja5060302