Inhibiting Epidermal Growth Factor Receptor at a Distance

[Image: see text] The epidermal growth factor receptor (EGFR) tyrosine kinase is implicated in a large number of human cancers. Most EGFR inhibitors target the extracellular, growth factor-binding domain or the intracellular, ATP-binding domain. Here we describe molecules that inhibit the kinase act...

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Detalles Bibliográficos
Autores principales: Sinclair, Julie K.-L., Denton, Elizabeth V., Schepartz, Alanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140499/
https://www.ncbi.nlm.nih.gov/pubmed/25075632
http://dx.doi.org/10.1021/ja504076t

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140499/
https://www.ncbi.nlm.nih.gov/pubmed/25075632
http://dx.doi.org/10.1021/ja504076t

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