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Solid-Phase Bioconjugation of Heterobifunctional Adaptors for Versatile Assembly of Bispecific Targeting Ligands

[Image: see text] High-throughput generation of bispecific molecules promises to expedite the discovery of new molecular therapeutics and guide engineering of novel multifunctional constructs. However, high synthesis complexity and cost have hampered the discovery of bispecific molecules in drug dev...

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Detalles Bibliográficos
Autores principales: Liu, Hong Yan, Zrazhevskiy, Pavel, Gao, Xiaohu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140535/
https://www.ncbi.nlm.nih.gov/pubmed/25010411
http://dx.doi.org/10.1021/bc5002455