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Solid-Phase Bioconjugation of Heterobifunctional Adaptors for Versatile Assembly of Bispecific Targeting Ligands
[Image: see text] High-throughput generation of bispecific molecules promises to expedite the discovery of new molecular therapeutics and guide engineering of novel multifunctional constructs. However, high synthesis complexity and cost have hampered the discovery of bispecific molecules in drug dev...
Autores principales: | Liu, Hong Yan, Zrazhevskiy, Pavel, Gao, Xiaohu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140535/ https://www.ncbi.nlm.nih.gov/pubmed/25010411 http://dx.doi.org/10.1021/bc5002455 |
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