Dextran as a Generally Applicable Multivalent Scaffold for Improving Immunoglobulin-Binding Affinities of Peptide and Peptidomimetic Ligands

[Image: see text] Molecules able to bind the antigen-binding sites of antibodies are of interest in medicine and immunology. Since most antibodies are bivalent, higher affinity recognition can be achieved through avidity effects in which a construct containing two or more copies of the ligand engage...

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Detalles Bibliográficos
Autores principales: Morimoto, Jumpei, Sarkar, Mohosin, Kenrick, Sophia, Kodadek, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140544/
https://www.ncbi.nlm.nih.gov/pubmed/25073654
http://dx.doi.org/10.1021/bc500226j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140544/
https://www.ncbi.nlm.nih.gov/pubmed/25073654
http://dx.doi.org/10.1021/bc500226j

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