A New Model for Pore Formation by Cholesterol-Dependent Cytolysins

Cholesterol Dependent Cytolysins (CDCs) are important bacterial virulence factors that form large (200–300 Å) membrane embedded pores in target cells. Currently, insights from X-ray crystallography, biophysical and single particle cryo-Electron Microscopy (cryo-EM) experiments suggest that soluble m...

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Detalles Bibliográficos
Autores principales: Reboul, Cyril F., Whisstock, James C., Dunstone, Michelle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140638/
https://www.ncbi.nlm.nih.gov/pubmed/25144725
http://dx.doi.org/10.1371/journal.pcbi.1003791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140638/
https://www.ncbi.nlm.nih.gov/pubmed/25144725
http://dx.doi.org/10.1371/journal.pcbi.1003791

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