Cargando…

A New Model for Pore Formation by Cholesterol-Dependent Cytolysins

Cholesterol Dependent Cytolysins (CDCs) are important bacterial virulence factors that form large (200–300 Å) membrane embedded pores in target cells. Currently, insights from X-ray crystallography, biophysical and single particle cryo-Electron Microscopy (cryo-EM) experiments suggest that soluble m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Reboul, Cyril F., Whisstock, James C., Dunstone, Michelle A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140638/ https://www.ncbi.nlm.nih.gov/pubmed/25144725 http://dx.doi.org/10.1371/journal.pcbi.1003791

Ejemplares similares

Stepwise visualization of membrane pore formation by suilysin, a bacterial cholesterol-dependent cytolysin
por: Leung, Carl, et al.
Publicado: (2014)

Correction: Stepwise visualization of membrane pore formation by suilysin, a bacterial cholesterol-dependent cytolysin
por: Leung, Carl, et al.
Publicado: (2015)

More Than a Pore: The Cellular Response to Cholesterol-Dependent Cytolysins
por: Cassidy, Sara K. B., et al.
Publicado: (2013)

Direct Transmembrane Interaction between Actin and the Pore-Competent, Cholesterol-Dependent Cytolysin Pneumolysin
por: Hupp, Sabrina, et al.
Publicado: (2013)

Editorial: Perforins and Cholesterol-Dependent Cytolysins in Immunity and Pathogenesis
por: Munson, George P., et al.
Publicado: (2022)

All major cholesterol-dependent cytolysins use glycans as cellular receptors
por: Shewell, Lucy K., et al.
Publicado: (2020)

The Cholesterol-Dependent Cytolysin Signature Motif: A Critical Element in the Allosteric Pathway that Couples Membrane Binding to Pore Assembly
por: Dowd, Kelley J., et al.
Publicado: (2012)

Cholesterol-dependent cytolysins impair pro-inflammatory macrophage responses
por: Bhattacharjee, Pushpak, et al.
Publicado: (2018)

Manipulating the Lewis antigen specificity of the cholesterol-dependent cytolysin lectinolysin
por: Lawrence, Sara L., et al.
Publicado: (2012)

Changes in Astrocyte Shape Induced by Sublytic Concentrations of the Cholesterol-Dependent Cytolysin Pneumolysin Still Require Pore-Forming Capacity
por: Förtsch, Christina, et al.
Publicado: (2011)

Cholesterol-Dependent Cytolysins Produced by Vaginal Bacteria: Certainties and Controversies
por: Pleckaityte, Milda
Publicado: (2020)

Molecular Mechanisms of Mast Cell Activation by Cholesterol-Dependent Cytolysins
por: Draberova, Lubica, et al.
Publicado: (2021)

Arcanolysin is a cholesterol-dependent cytolysin of the human pathogen Arcanobacterium haemolyticum
por: Jost, B Helen, et al.
Publicado: (2011)

Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin
por: Lukoyanova, Natalya, et al.
Publicado: (2015)

Correction: The Cholesterol-Dependent Cytolysin Signature Motif: A Critical Element in the Allosteric Pathway that Couples Membrane Binding to Pore Assembly
por: Dowd, Kelley J., et al.
Publicado: (2012)

Glu289 residue in the pore-forming motif of Vibrio cholerae cytolysin is important for efficient β-barrel pore formation
por: Mondal, Anish Kumar, et al.
Publicado: (2022)

A Key Motif in the Cholesterol-Dependent Cytolysins Reveals a Large Family of Related Proteins
por: Evans, Jordan C., et al.
Publicado: (2020)

Protective role of the dynamin inhibitor Dynasore against the cholesterol-dependent cytolysin of Trueperella pyogenes
por: Preta, Giulio, et al.
Publicado: (2015)

Alteration of epithelial cell lysosomal integrity induced by bacterial cholesterol‐dependent cytolysins
por: Malet, Julien Karim, et al.
Publicado: (2016)

Reprogramming cholesterol metabolism in macrophages and its role in host defense against cholesterol-dependent cytolysins
por: Lee, Min-Sub, et al.
Publicado: (2022)

Interaction of Macrophages and Cholesterol-Dependent Cytolysins: The Impact on Immune Response and Cellular Survival
por: Thapa, Roshan, et al.
Publicado: (2020)

The Bacillus anthracis cholesterol-dependent cytolysin, Anthrolysin O, kills human neutrophils, monocytes and macrophages
por: Mosser, Elise M, et al.
Publicado: (2006)

Multiple Parameters Beyond Lipid Binding Affinity Drive Cytotoxicity of Cholesterol-Dependent Cytolysins
por: Ray, Sucharit, et al.
Publicado: (2018)

Membrane repair triggered by cholesterol-dependent cytolysins is activated by mixed lineage kinases and MEK
por: Ray, Sucharit, et al.
Publicado: (2022)

An oomycete NLP cytolysin forms transient small pores in lipid membranes
por: Pirc, Katja, et al.
Publicado: (2022)

Crystal structure of an invertebrate cytolysin pore reveals unique properties and mechanism of assembly
por: Podobnik, Marjetka, et al.
Publicado: (2016)

Inhibiting mevalonate pathway enzymes increases stromal cell resilience to a cholesterol-dependent cytolysin
por: Griffin, Sholeem, et al.
Publicado: (2017)

Prediction of B-Cell Epitopes in Listeriolysin O, a Cholesterol Dependent Cytolysin Secreted by Listeria monocytogenes
por: Jones, Morris S., et al.
Publicado: (2014)

Isoprenoids increase bovine endometrial stromal cell tolerance to the cholesterol-dependent cytolysin from Trueperella pyogenes
por: Griffin, Sholeem, et al.
Publicado: (2018)

Arcanobacterium haemolyticum Phospholipase D Enzymatic Activity Promotes the Hemolytic Activity of the Cholesterol-Dependent Cytolysin Arcanolysin
por: Gellings, Patrick S., et al.
Publicado: (2018)

Glutamine supports the protection of tissue cells against the damage caused by cholesterol-dependent cytolysins from pathogenic bacteria
por: Turner, Matthew L., et al.
Publicado: (2020)

Curcumin Inhibits Membrane-Damaging Pore-Forming Function of the β-Barrel Pore-Forming Toxin Vibrio cholerae Cytolysin
por: Singh, Mahendra, et al.
Publicado: (2022)

The Cholesterol-Dependent Cytolysin Pneumolysin from Streptococcus pneumoniae Binds to Lipid Raft Microdomains in Human Corneal Epithelial Cells
por: Taylor, Sidney D., et al.
Publicado: (2013)

The MACPF/CDC family of pore-forming toxins
por: Rosado, Carlos J, et al.
Publicado: (2008)

Slow Escape from a Helical Misfolded State of the Pore-Forming Toxin Cytolysin A
por: Dingfelder, Fabian, et al.
Publicado: (2021)

Single-molecule analysis of the entire perfringolysin O pore formation pathway
por: McGuinness, Conall, et al.
Publicado: (2022)

The Pore-Forming Toxin β hemolysin/cytolysin Triggers p38 MAPK-Dependent IL-10 Production in Macrophages and Inhibits Innate Immunity
por: Bebien, Magali, et al.
Publicado: (2012)

Fish Cytolysins in All Their Complexity
por: Campos, Fabiana V., et al.
Publicado: (2021)

Ancient but Not Forgotten: New Insights Into MPEG1, a Macrophage Perforin-Like Immune Effector
por: Bayly-Jones, Charles, et al.
Publicado: (2020)

Cells Responding to Closely Related Cholesterol-Dependent Cytolysins Release Extracellular Vesicles with a Common Proteomic Content Including Membrane Repair Proteins
por: Alves, Sara, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_mejuvuudv2pofjar8bgqk29ni3