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A Model-Based Approach for Identifying Signatures of Ancient Balancing Selection in Genetic Data

While much effort has focused on detecting positive and negative directional selection in the human genome, relatively little work has been devoted to balancing selection. This lack of attention is likely due to the paucity of sophisticated methods for identifying sites under balancing selection. He...

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Detalles Bibliográficos
Autores principales: DeGiorgio, Michael, Lohmueller, Kirk E., Nielsen, Rasmus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140648/
https://www.ncbi.nlm.nih.gov/pubmed/25144706
http://dx.doi.org/10.1371/journal.pgen.1004561