Schistosoma japonicum Soluble Egg Antigens Facilitate Hepatic Stellate Cell Apoptosis by Downregulating Akt Expression and Upregulating p53 and DR5 Expression

BACKGROUND: The induction of hepatic stellate cell (HSC) apoptosis has potential as a potent strategy to diminish the progression of liver fibrosis. Previous studies have demonstrated the ability of soluble egg antigens (SEA) from schistosomes to inhibit HSC activation and to induce apoptosis in vit...

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Detalles Bibliográficos
Autores principales: Wang, Jianxin, Xu, Feifan, Zhu, Dandan, Duan, Yinong, Chen, Jinling, Sun, Xiaolei, He, Xue, Li, Pan, Sun, Wei, Feng, Jinrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140669/
https://www.ncbi.nlm.nih.gov/pubmed/25144704
http://dx.doi.org/10.1371/journal.pntd.0003106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140669/
https://www.ncbi.nlm.nih.gov/pubmed/25144704
http://dx.doi.org/10.1371/journal.pntd.0003106

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