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A Panel of Trypanosoma brucei Strains Tagged with Blue and Red-Shifted Luciferases for Bioluminescent Imaging in Murine Infection Models

BACKGROUND: Genetic engineering with luciferase reporter genes allows monitoring Trypanosoma brucei (T.b.) infections in mice by in vivo bioluminescence imaging (BLI). Until recently, luminescent T.b. models were based on Renilla luciferase (RLuc) activity. Our study aimed at evaluating red-shifted...

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Detalles Bibliográficos
Autores principales: Van Reet, Nick, Van de Vyver, Hélène, Pyana, Patient Pati, Van der Linden, Anne Marie, Büscher, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140678/
https://www.ncbi.nlm.nih.gov/pubmed/25144573
http://dx.doi.org/10.1371/journal.pntd.0003054