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Monitoring the Initiation and Kinetics of Human Dendritic Cell-Induced Polarization of Autologous Naive CD4(+) T Cells

A crucial step in generating de novo immune responses is the polarization of naive cognate CD4(+) T cells by pathogen-triggered dendritic cells (DC). In the human setting, standardized DC-dependent systems are lacking to study molecular events during the initiation of a naive CD4(+) T cell response....

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Detalles Bibliográficos
Autores principales: Oth, Tammy, Schnijderberg, Melanie C. A., Senden-Gijsbers, Birgit L. M. G., Germeraad, Wilfred T. V., Bos, Gerard M. J., Vanderlocht, Joris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140687/
https://www.ncbi.nlm.nih.gov/pubmed/25144736
http://dx.doi.org/10.1371/journal.pone.0103725