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Monitoring the Initiation and Kinetics of Human Dendritic Cell-Induced Polarization of Autologous Naive CD4(+) T Cells
A crucial step in generating de novo immune responses is the polarization of naive cognate CD4(+) T cells by pathogen-triggered dendritic cells (DC). In the human setting, standardized DC-dependent systems are lacking to study molecular events during the initiation of a naive CD4(+) T cell response....
Autores principales: | Oth, Tammy, Schnijderberg, Melanie C. A., Senden-Gijsbers, Birgit L. M. G., Germeraad, Wilfred T. V., Bos, Gerard M. J., Vanderlocht, Joris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140687/ https://www.ncbi.nlm.nih.gov/pubmed/25144736 http://dx.doi.org/10.1371/journal.pone.0103725 |
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