Cargando…
Detection of MPLW515L/K Mutations and Determination of Allele Frequencies with a Single-Tube PCR Assay
A gain-of-function mutation in the myeloproliferative leukemia virus (MPL) gene, which encodes the thrombopoietin receptor, has been identified in patients with essential thrombocythemia and primary myelofibrosis, subgroups of classic myeloproliferative neoplasms (MPNs). The presence of MPL gene mut...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140728/ https://www.ncbi.nlm.nih.gov/pubmed/25144224 http://dx.doi.org/10.1371/journal.pone.0104958 |