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Detection of MPLW515L/K Mutations and Determination of Allele Frequencies with a Single-Tube PCR Assay

A gain-of-function mutation in the myeloproliferative leukemia virus (MPL) gene, which encodes the thrombopoietin receptor, has been identified in patients with essential thrombocythemia and primary myelofibrosis, subgroups of classic myeloproliferative neoplasms (MPNs). The presence of MPL gene mut...

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Detalles Bibliográficos
Autores principales:	Takei, Hiraku, Morishita, Soji, Araki, Marito, Edahiro, Yoko, Sunami, Yoshitaka, Hironaka, Yumi, Noda, Naohiro, Sekiguchi, Yuji, Tsuneda, Satoshi, Ohsaka, Akimichi, Komatsu, Norio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140728/ https://www.ncbi.nlm.nih.gov/pubmed/25144224 http://dx.doi.org/10.1371/journal.pone.0104958

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