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Pterostilbene Simultaneously Induced G0/G1-Phase Arrest and MAPK-Mediated Mitochondrial-Derived Apoptosis in Human Acute Myeloid Leukemia Cell Lines

BACKGROUND: Pterostilbene (PTER) is a dimethylated analog of the phenolic phytoalexin, resveratrol, with higher anticancer activity in various tumors. Herein, the molecular mechanisms by which PTER exerts its anticancer effects against acute myeloid leukemia (AML) cells were investigated. METHODOLOG...

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Detalles Bibliográficos
Autores principales: Hsiao, Pei-Ching, Chou, Ying-Erh, Tan, Peng, Lee, Wei-Jiunn, Yang, Shun-Fa, Chow, Jyh-Ming, Chen, Hui-Yu, Lin, Chien-Huang, Lee, Liang-Ming, Chien, Ming-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140770/
https://www.ncbi.nlm.nih.gov/pubmed/25144448
http://dx.doi.org/10.1371/journal.pone.0105342