Cargando…

Pterostilbene Simultaneously Induced G0/G1-Phase Arrest and MAPK-Mediated Mitochondrial-Derived Apoptosis in Human Acute Myeloid Leukemia Cell Lines

BACKGROUND: Pterostilbene (PTER) is a dimethylated analog of the phenolic phytoalexin, resveratrol, with higher anticancer activity in various tumors. Herein, the molecular mechanisms by which PTER exerts its anticancer effects against acute myeloid leukemia (AML) cells were investigated. METHODOLOG...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hsiao, Pei-Ching, Chou, Ying-Erh, Tan, Peng, Lee, Wei-Jiunn, Yang, Shun-Fa, Chow, Jyh-Ming, Chen, Hui-Yu, Lin, Chien-Huang, Lee, Liang-Ming, Chien, Ming-Hsien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140770/ https://www.ncbi.nlm.nih.gov/pubmed/25144448 http://dx.doi.org/10.1371/journal.pone.0105342

Ejemplares similares

Penfluridol triggers cytoprotective autophagy and cellular apoptosis through ROS induction and activation of the PP2A-modulated MAPK pathway in acute myeloid leukemia with different FLT3 statuses
por: Wu, Szu-Yuan, et al.
Publicado: (2019)

The Curcumin Analogue, EF-24, Triggers p38 MAPK-Mediated Apoptotic Cell Death via Inducing PP2A-Modulated ERK Deactivation in Human Acute Myeloid Leukemia Cells
por: Hsiao, Pei-Ching, et al.
Publicado: (2020)

Tricetin Induces Apoptosis of Human Leukemic HL-60 Cells through a Reactive Oxygen Species-Mediated c-Jun N-Terminal Kinase Activation Pathway
por: Chien, Ming-Hsien, et al.
Publicado: (2017)

Activation of PERK Contributes to Apoptosis and G(2)/M Arrest by Microtubule Disruptors in Human Colorectal Carcinoma Cells
por: Wu, Ming-Shun, et al.
Publicado: (2019)

Combined Effects of ICAM-1 Single-Nucleotide Polymorphisms and Environmental Carcinogens on Oral Cancer Susceptibility and Clinicopathologic Development
por: Lin, Chiao-Wen, et al.
Publicado: (2013)

Effects of MACC1 polymorphisms on hepatocellular carcinoma development and clinical characteristics
por: Lin, Chien-Hua, et al.
Publicado: (2020)

By inhibiting snail signaling and miR-23a-3p, osthole suppresses the EMT-mediated metastatic ability in prostate cancer
por: Wen, Yu-Ching, et al.
Publicado: (2015)

Glabridin Mediate Caspases Activation and Induces Apoptosis through JNK1/2 and p38 MAPK Pathway in Human Promyelocytic Leukemia Cells
por: Huang, Hsin-Lien, et al.
Publicado: (2014)

Roles of reactive oxygen species, mitochondrial membrane potential, and p53 in evodiamine-induced apoptosis and G2/M arrest of human anaplastic thyroid carcinoma cells
por: Chien, Chih-Chiang, et al.
Publicado: (2021)

Luteoloside Induces G0/G1 Phase Arrest of Neuroblastoma Cells by Targeting p38 MAPK
por: He, Ya, et al.
Publicado: (2023)

Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and subsequent metastatic ability in human osteosarcomas
por: Yang, Shun-Fa, et al.
Publicado: (2014)

Nonautophagic cytoplasmic vacuolation death induction in human PC-3M prostate cancer by curcumin through reactive oxygen species -mediated endoplasmic reticulum stress
por: Lee, Wei-Jiunn, et al.
Publicado: (2015)

Corrigendum: Nonautophagic cytoplasmic vacuolation death induction in human PC-3M prostate cancer by curcumin through reactive oxygen species -mediated endoplasmic reticulum stress
por: Lee, Wei-Jiunn, et al.
Publicado: (2017)

Dual Targeting of the p38 MAPK-HO-1 Axis and cIAP1/XIAP by Demethoxycurcumin Triggers Caspase-Mediated Apoptotic Cell Death in Oral Squamous Cell Carcinoma Cells
por: Chien, Ming-Hsien, et al.
Publicado: (2020)

Propranolol induced G0/G1/S phase arrest and apoptosis in melanoma cells via AKT/MAPK pathway
por: Zhou, Chengfang, et al.
Publicado: (2016)

Association of EGFR mutations and HMGB1 genetic polymorphisms in lung adenocarcinoma patients
por: Wu, Yi-Liang, et al.
Publicado: (2019)

Activation of JNK Contributes to Evodiamine-Induced Apoptosis and G(2)/M Arrest in Human Colorectal Carcinoma Cells: A Structure-Activity Study of Evodiamine
por: Chien, Chih-Chiang, et al.
Publicado: (2014)

Impact of Clinicopathological Characteristics and Tissue Inhibitor of Metalloproteinase-3 Polymorphism Rs9619311 on Biochemical Recurrence in Taiwanese Patients with Prostate Cancer
por: Hsieh, Chun-Yu, et al.
Publicado: (2022)

Impact of Long Non-Coding RNA HOTAIR Genetic Variants on the Susceptibility and Clinicopathologic Characteristics of Patients with Urothelial Cell Carcinoma
por: Tung, Min-Che, et al.
Publicado: (2019)

Enhancement of Anticancer Potential of Pterostilbene Derivative by Chalcone Hybridization
por: Tang, Kai-Wei, et al.
Publicado: (2021)

Histone Methyltransferase G9a-Promoted Progression of Hepatocellular Carcinoma Is Targeted by Liver-Specific Hsa-miR-122
por: Yuan, Lan-Ting, et al.
Publicado: (2021)

Downregulating CD26/DPPIV by apigenin modulates the interplay between Akt and Snail/Slug signaling to restrain metastasis of lung cancer with multiple EGFR statuses
por: Chang, Jer-Hwa, et al.
Publicado: (2018)

Correlation of Chitinase 3-Like 1 Single Nucleotide Polymorphisms and Haplotypes with Uterine Cervical Cancer in Taiwanese Women
por: Lin, Yue-Shan, et al.
Publicado: (2014)

Apoptotic and Nonapoptotic Activities of Pterostilbene against Cancer
por: Chen, Rong-Jane, et al.
Publicado: (2018)

Pterostilbene enhances sorafenib’s anticancer effects on gastric adenocarcinoma
por: Zhao, Tingting, et al.
Publicado: (2020)

Associations of VEGF-C Genetic Polymorphisms with Urothelial Cell Carcinoma Susceptibility Differ between Smokers and Non-Smokers in Taiwan
por: Tung, Min-Che, et al.
Publicado: (2014)

Chinese Herbal Mixture, Tien-Hsien Liquid, Induces G2/M Cycle Arrest and Radiosensitivity in MCF-7 Human Breast Cancer Cells through Mechanisms Involving DNMT1 and Rad51 Downregulation
por: Yao, Chih-Jung, et al.
Publicado: (2016)

Interactions between Environmental Factors and Melatonin Receptor Type 1A Polymorphism in Relation to Oral Cancer Susceptibility and Clinicopathologic Development
por: Lin, Feng-Yan, et al.
Publicado: (2015)

Advanced Oxidation Protein Products Induce G1/G0-Phase Arrest in Ovarian Granulosa Cells via the ROS-JNK/p38 MAPK-p21 Pathway in Premature Ovarian Insufficiency
por: Zhou, Xing-Yu, et al.
Publicado: (2021)

Modulation of macrophage polarization and lung cancer cell stemness by MUC1 and development of a related small-molecule inhibitor pterostilbene
por: Huang, Wen-Chien, et al.
Publicado: (2016)

Stimulation of ROS Generation by Extract of Warburgia ugandensis Leading to G(0)/G(1) Cell Cycle Arrest and Antiproliferation in A549 Cells
por: Zhang, Yong-Li, et al.
Publicado: (2021)

The Dose-Dependent Immunoregulatory Effects of the Nitric Oxide Synthase Inhibitor N(G)-Nitro-L-Arginine Methyl Ester in Rats with Sub-Acute Peritonitis
por: Hsiao, Chien-Chou, et al.
Publicado: (2012)

Polymorphic G:G mismatches act as hotspots for inducing right-handed Z DNA by DNA intercalation
por: Satange, Roshan, et al.
Publicado: (2019)

A new Prenylated Flavonoid induces G0/G1 arrest and apoptosis through p38/JNK MAPK pathways in Human Hepatocellular Carcinoma cells
por: Wang, Di, et al.
Publicado: (2017)

Impact of Matrix Metalloproteinase-11 Gene Polymorphisms on Biochemical Recurrence and Clinicopathological Characteristics of Prostate Cancer
por: Hsieh, Chun-Yu, et al.
Publicado: (2020)

Pterostilbene in Cancer Therapy
por: Obrador, Elena, et al.
Publicado: (2021)

MALDI Mass Spectrometry Imaging for the Simultaneous Location of Resveratrol, Pterostilbene and Viniferins on Grapevine Leaves
por: Becker, Loïc, et al.
Publicado: (2014)

Pterostilbene Sensitizes Cisplatin-Resistant Human Bladder Cancer Cells with Oncogenic HRAS
por: Chen, Yi-Ting, et al.
Publicado: (2020)

Functional genetic variant of WW domain-containing oxidoreductase (WWOX) gene is associated with hepatocellular carcinoma risk
por: Lee, Hsiang-Lin, et al.
Publicado: (2017)

Tectorigenin Inhibits Glioblastoma Proliferation by G0/G1 Cell Cycle Arrest
por: Yeh, Liang-Tsai, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_53t968ceoq0a7cr81qfgoo2gi9