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Histone Deacetylase 3 Promotes RCAN1 Stability and Nuclear Translocation

Regulator of calcineurin 1 (RCAN1; also referred as DSCR1 or MCIP1) is located in close proximity to a Down syndrome critical region of human chromosome 21. Although RCAN1 is an endogenous inhibitor of calcineurin signaling that controls lymphocyte activation, apoptosis, heart development, skeletal...

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Detalles Bibliográficos
Autores principales: Han, Kyung Ah, Kang, Hye Seon, Lee, Jee Won, Yoo, Lang, Im, Eunju, Hong, Ahyoung, Lee, Yun Ju, Shin, Woo Hyun, Chung, Kwang Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140772/
https://www.ncbi.nlm.nih.gov/pubmed/25144594
http://dx.doi.org/10.1371/journal.pone.0105416