The Effect of (-)-Epigallocatechin 3-O - Gallate In Vitro and In Vivo in Leishmania braziliensis: Involvement of Reactive Oxygen Species as a Mechanism of Action

BACKGROUND: Leishmaniasis is a parasitic disease associated with extensive mortality and morbidity. The treatment for leishmaniasis is currently based on pentavalent antimonials and amphotericin B; however, these drugs result in numerous adverse side effects. Natural compounds have been used as nove...

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Detalles Bibliográficos
Autores principales: Inacio, Job D. F., Gervazoni, Luiza, Canto-Cavalheiro, Marilene M., Almeida-Amaral, Elmo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140776/
https://www.ncbi.nlm.nih.gov/pubmed/25144225
http://dx.doi.org/10.1371/journal.pntd.0003093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140776/
https://www.ncbi.nlm.nih.gov/pubmed/25144225
http://dx.doi.org/10.1371/journal.pntd.0003093

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