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The Effect of (-)-Epigallocatechin 3-O - Gallate In Vitro and In Vivo in Leishmania braziliensis: Involvement of Reactive Oxygen Species as a Mechanism of Action
BACKGROUND: Leishmaniasis is a parasitic disease associated with extensive mortality and morbidity. The treatment for leishmaniasis is currently based on pentavalent antimonials and amphotericin B; however, these drugs result in numerous adverse side effects. Natural compounds have been used as nove...
Autores principales: | Inacio, Job D. F., Gervazoni, Luiza, Canto-Cavalheiro, Marilene M., Almeida-Amaral, Elmo E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140776/ https://www.ncbi.nlm.nih.gov/pubmed/25144225 http://dx.doi.org/10.1371/journal.pntd.0003093 |
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