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Rosiglitazone Inhibits TGF-β 1 Induced Activation of Human Tenon Fibroblasts via p38 Signal Pathway

PURPOSE: Transdifferentiation of human Tenon fibroblasts to myofibroblasts and subsequent deposition of extracellular matrix is a key step in the scarring after glaucoma filtration surgery. The p38 signaling pathway plays an important role in cell proliferation and differentiation, and its upstream...

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Detalles Bibliográficos
Autores principales: Luo, Yong-Heng, Ouyang, Ping-Bo, Tian, Jiao, Guo, Xiao-Jian, Duan, Xuan-Chu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140818/
https://www.ncbi.nlm.nih.gov/pubmed/25144187
http://dx.doi.org/10.1371/journal.pone.0105796