Cargando…
Structural and Biochemical Characterization of the Cop9 Signalosome CSN5/CSN6 Heterodimer
The Cop9 signalosome complex (CSN) regulates the functional cycle of the major E3 ubiquitin ligase family, the cullin RING E3 ubiquitin ligases (CRLs). Activated CRLs are covalently modified by the ubiquitin-like protein Nedd8 (neural precursor cell expressed developmentally down-regulated protein 8...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140821/ https://www.ncbi.nlm.nih.gov/pubmed/25144743 http://dx.doi.org/10.1371/journal.pone.0105688 |