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Structural and Biochemical Characterization of the Cop9 Signalosome CSN5/CSN6 Heterodimer

The Cop9 signalosome complex (CSN) regulates the functional cycle of the major E3 ubiquitin ligase family, the cullin RING E3 ubiquitin ligases (CRLs). Activated CRLs are covalently modified by the ubiquitin-like protein Nedd8 (neural precursor cell expressed developmentally down-regulated protein 8...

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Detalles Bibliográficos
Autores principales:	Birol, Melissa, Enchev, Radoslav Ivanov, Padilla, André, Stengel, Florian, Aebersold, Ruedi, Betzi, Stéphane, Yang, Yinshan, Hoh, François, Peter, Matthias, Dumas, Christian, Echalier, Aude
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140821/ https://www.ncbi.nlm.nih.gov/pubmed/25144743 http://dx.doi.org/10.1371/journal.pone.0105688

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