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Linear Associations between Clinically Assessed Upper Motor Neuron Disease and Diffusion Tensor Imaging Metrics in Amyotrophic Lateral Sclerosis

OBJECTIVE: To assess the relationship between clinically assessed Upper Motor Neuron (UMN) disease in Amyotrophic Lateral Sclerosis (ALS) and local diffusion alterations measured in the brain corticospinal tract (CST) by a tractography-driven template-space region-of-interest (ROI) analysis of Diffu...

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Detalles Bibliográficos
Autores principales: Woo, John H., Wang, Sumei, Melhem, Elias R., Gee, James C., Cucchiara, Andrew, McCluskey, Leo, Elman, Lauren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140827/
https://www.ncbi.nlm.nih.gov/pubmed/25144708
http://dx.doi.org/10.1371/journal.pone.0105753