Neuroantigen-Specific Autoregulatory CD8+ T Cells Inhibit Autoimmune Demyelination through Modulation of Dendritic Cell Function

Experimental autoimmune encephalomyelitis (EAE) is a well-established murine model of multiple sclerosis, an immune-mediated demyelinating disorder of the central nervous system (CNS). We have previously shown that CNS-specific CD8+ T cells (CNS-CD8+) ameliorate EAE, at least in part through modulat...

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Detalles Bibliográficos
Autores principales: Kashi, Venkatesh P., Ortega, Sterling B., Karandikar, Nitin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140828/
https://www.ncbi.nlm.nih.gov/pubmed/25144738
http://dx.doi.org/10.1371/journal.pone.0105763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140828/
https://www.ncbi.nlm.nih.gov/pubmed/25144738
http://dx.doi.org/10.1371/journal.pone.0105763

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