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Small RNA Sequence Analysis of Adenovirus VA RNA-Derived MiRNAs Reveals an Unexpected Serotype-Specific Difference in Structure and Abundance

Human adenoviruses (HAds) encode for one or two highly abundant virus-associated RNAs, designated VA RNAI and VA RNAII, which fold into stable hairpin structures resembling miRNA precursors. Here we show that the terminal stem of the VA RNAs originating from Ad4, Ad5, Ad11 and Ad37, all undergo Dice...

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Detalles Bibliográficos
Autores principales: Kamel, Wael, Segerman, Bo, Punga, Tanel, Akusjärvi, Göran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140831/
https://www.ncbi.nlm.nih.gov/pubmed/25144466
http://dx.doi.org/10.1371/journal.pone.0105746