CYP2W1 Is Highly Expressed in Adrenal Glands and Is Positively Associated with the Response to Mitotane in Adrenocortical Carcinoma

BACKGROUND: Adrenocortical tumors comprise frequent adenomas (ACA) and rare carcinomas (ACC). Human cytochrome P450 2W1 (CYP2W1) is highly expressed in some cancers holding the potential to activate certain drugs into tumor cytotoxins. OBJECTIVE: To investigate the CYP2W1 expression in adrenal sampl...

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Detalles Bibliográficos
Autores principales: Ronchi, Cristina L., Sbiera, Silviu, Volante, Marco, Steinhauer, Sonja, Scott-Wild, Vanessa, Altieri, Barbara, Kroiss, Matthias, Bala, Margarita, Papotti, Mauro, Deutschbein, Timo, Terzolo, Massimo, Fassnacht, Martin, Allolio, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140842/
https://www.ncbi.nlm.nih.gov/pubmed/25144458
http://dx.doi.org/10.1371/journal.pone.0105855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140842/
https://www.ncbi.nlm.nih.gov/pubmed/25144458
http://dx.doi.org/10.1371/journal.pone.0105855

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