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Production of an Attenuated Phenol-Soluble Modulin Variant Unique to the MRSA Clonal Complex 30 Increases Severity of Bloodstream Infection

Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of morbidity and death. Phenol-soluble modulins (PSMs) are recently-discovered toxins with a key impact on the development of Staphylococcus aureus infections. Allelic variants of PSMs and their potential impact on pathogen succes...

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Detalles Bibliográficos
Autores principales: Cheung, Gordon Y. C., Kretschmer, Dorothee, Duong, Anthony C., Yeh, Anthony J., Ho, Trung V., Chen, Yan, Joo, Hwang-Soo, Kreiswirth, Barry N., Peschel, Andreas, Otto, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140855/
https://www.ncbi.nlm.nih.gov/pubmed/25144687
http://dx.doi.org/10.1371/journal.ppat.1004298