Cargando…

Production of an Attenuated Phenol-Soluble Modulin Variant Unique to the MRSA Clonal Complex 30 Increases Severity of Bloodstream Infection

Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of morbidity and death. Phenol-soluble modulins (PSMs) are recently-discovered toxins with a key impact on the development of Staphylococcus aureus infections. Allelic variants of PSMs and their potential impact on pathogen succes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheung, Gordon Y. C., Kretschmer, Dorothee, Duong, Anthony C., Yeh, Anthony J., Ho, Trung V., Chen, Yan, Joo, Hwang-Soo, Kreiswirth, Barry N., Peschel, Andreas, Otto, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140855/ https://www.ncbi.nlm.nih.gov/pubmed/25144687 http://dx.doi.org/10.1371/journal.ppat.1004298

Ejemplares similares

Interaction of Phenol-Soluble Modulins with Phosphatidylcholine Vesicles
por: Duong, Anthony C., et al.
Publicado: (2012)

Phenol-soluble modulins in staphylococci: What are they originally for?
por: Periasamy, Saravanan, et al.
Publicado: (2012)

Phenol-Soluble Modulin Toxins of Staphylococcus haemolyticus
por: Da, Fei, et al.
Publicado: (2017)

Staphylococcus aureus Depends on Eap Proteins for Preventing Degradation of Its Phenol-Soluble Modulin Toxins by Neutrophil Serine Proteases
por: Kretschmer, Dorothee, et al.
Publicado: (2021)

Distribution and Regulation of the Mobile Genetic Element-Encoded Phenol-Soluble Modulin PSM-mec in Methicillin-Resistant Staphylococcus aureus
por: Chatterjee, Som S., et al.
Publicado: (2011)

The Mechanism behind Bacterial Lipoprotein Release: Phenol-Soluble Modulins Mediate Toll-Like Receptor 2 Activation via Extracellular Vesicle Release from Staphylococcus aureus
por: Schlatterer, Katja, et al.
Publicado: (2018)

Inactivation of Staphylococcal Phenol Soluble Modulins by Serum Lipoprotein Particles
por: Surewaard, Bas G. J., et al.
Publicado: (2012)

Identification and characterization of the pathogenic potential of phenol-soluble modulin toxins in the mouse commensal Staphylococcus xylosus
por: Reshamwala, Kunal, et al.
Publicado: (2022)

Expression and regulation of phenol-soluble modulins and enterotoxins in foodborne Staphylococcus aureus
por: Wu, Xiaoxiao, et al.
Publicado: (2018)

Phenol-Soluble Modulins Modulate Persister Cell Formation in Staphylococcus aureus
por: Baldry, Mara, et al.
Publicado: (2020)

High density lipoproteins mediate in vivo protection against staphylococcal phenol-soluble modulins
por: Hommes, Josefien W., et al.
Publicado: (2021)

Functional Amyloids Composed of Phenol Soluble Modulins Stabilize Staphylococcus aureus Biofilms
por: Schwartz, Kelly, et al.
Publicado: (2012)

Cell-Surface Phenol Soluble Modulins Regulate Staphylococcus aureus Colony Spreading
por: Kizaki, Hayato, et al.
Publicado: (2016)

Phenol-soluble modulin contributes to the dispersal of Staphylococcus epidermidis isolates from catheters
por: Jin, Yixin, et al.
Publicado: (2022)

Phenol-Soluble Modulin α3 Stimulates Autophagy in HaCaT Keratinocytes
por: Dernovics, Áron, et al.
Publicado: (2023)

Dissecting the contribution of Staphylococcus aureus α-phenol-soluble modulins to biofilm amyloid structure
por: Marinelli, Patrizia, et al.
Publicado: (2016)

Intracellular persistence of Staphylococcus aureus in endothelial cells is promoted by the absence of phenol-soluble modulins
por: Siegmund, Anke, et al.
Publicado: (2021)

Genotypes of Staphylococcus aureus Clinical Isolates Are Associated with Phenol-Soluble Modulin (PSM) Production
por: Lade, Harshad, et al.
Publicado: (2022)

Quorum Sensing-Regulated Phenol-Soluble Modulins Limit Persister Cell Populations in Staphylococcus aureus
por: Bojer, Martin S., et al.
Publicado: (2018)

Modulating Kinetics of the Amyloid-Like Aggregation of S. aureus Phenol-Soluble Modulins by Changes in pH
por: Zaman, Masihuz, et al.
Publicado: (2021)

The Bacterial Amyloids Phenol Soluble Modulins from Staphylococcus aureus Catalyze Alpha-Synuclein Aggregation
por: Haikal, Caroline, et al.
Publicado: (2021)

Human Fibrinogen Inhibits Amyloid Assembly of Most Phenol-Soluble Modulins from Staphylococcus aureus
por: Najarzadeh, Zahra, et al.
Publicado: (2021)

Heparin promotes fibrillation of most phenol-soluble modulin virulence peptides from Staphylococcus aureus
por: Najarzadeh, Zahra, et al.
Publicado: (2021)

Phenol-Soluble Modulins From Staphylococcus aureus Biofilms Form Complexes With DNA to Drive Autoimmunity
por: Grando, Kaitlyn, et al.
Publicado: (2022)

Thymol Reduces agr-Mediated Virulence Factor Phenol-Soluble Modulin Production in Staphylococcus aureus
por: Lade, Harshad, et al.
Publicado: (2022)

Phenol-soluble modulin α and β display divergent roles in mice with staphylococcal septic arthritis
por: Hu, Zhicheng, et al.
Publicado: (2022)

Mobile Genetic Element-Encoded Cytolysin Connects Virulence to Methicillin Resistance in MRSA
por: Queck, Shu Y., et al.
Publicado: (2009)

Phenol-Soluble Modulins Contribute to Early Sepsis Dissemination Not Late Local USA300-Osteomyelitis Severity in Rabbits
por: Davido, Benjamin, et al.
Publicado: (2016)

Delta Hemolysin and Phenol-Soluble Modulins, but Not Alpha Hemolysin or Panton-Valentine Leukocidin, Induce Mast Cell Activation
por: Hodille, Elisabeth, et al.
Publicado: (2016)

The Agr Quorum Sensing System Represses Persister Formation through Regulation of Phenol Soluble Modulins in Staphylococcus aureus
por: Xu, Tao, et al.
Publicado: (2017)

The Small RNA Teg41 Regulates Expression of the Alpha Phenol-Soluble Modulins and Is Required for Virulence in Staphylococcus aureus
por: Zapf, Rachel L., et al.
Publicado: (2019)

Phenol-Soluble Modulin-Mediated Aggregation of Community-Associated Methicillin-Resistant Staphylococcus Aureus in Human Cerebrospinal Fluid
por: Kim, Deok-ryeong, et al.
Publicado: (2020)

Phenol-soluble modulins PSMα3 and PSMβ2 form nanotubes that are cross-α amyloids
por: Kreutzberger, Mark A. B., et al.
Publicado: (2022)

Staphylococcus epidermidis activates keratinocyte cytokine expression and promotes skin inflammation through the production of phenol-soluble modulins
por: Williams, Michael R., et al.
Publicado: (2023)

Novel Regulation of Alpha-Toxin and the Phenol-Soluble Modulins by Peptidyl-Prolyl cis/trans Isomerase Enzymes in Staphylococcus aureus
por: Keogh, Rebecca A., et al.
Publicado: (2019)

Cross-talk between individual phenol-soluble modulins in Staphylococcus aureus biofilm enables rapid and efficient amyloid formation
por: Zaman, Masihuz, et al.
Publicado: (2020)

Phenol-soluble modulins α are major virulence factors of Staphylococcus aureus secretome promoting inflammatory response in human epidermis
por: Damour, Alexia, et al.
Publicado: (2021)

Effect of Bacterial Amyloid Protein Phenol−Soluble Modulin Alpha 3 on the Aggregation of Amyloid Beta Protein Associated with Alzheimer’s Disease
por: Peng, Bushu, et al.
Publicado: (2023)

Staphylococcus epidermidis Antimicrobial δ-Toxin (Phenol-Soluble Modulin-γ) Cooperates with Host Antimicrobial Peptides to Kill Group A Streptococcus
por: Cogen, Anna L., et al.
Publicado: (2010)

Phenol-soluble modulin α4 mediates Staphylococcus aureus-associated vascular leakage by stimulating heparin-binding protein release from neutrophils
por: li, Lin, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_iu1a77b6qrjtvnpslfs8q4t82n